Mitochondrial dynamics: Biological roles, molecular machinery, and related diseases

AW El-Hattab, J Suleiman, M Almannai… - Molecular genetics and …, 2018 - Elsevier
Mitochondria are dynamic organelles that undergo fusion, fission, movement, and
mitophagy. These processes are essential to maintain the normal mitochondrial
morphology, distribution, and function. Mitochondrial fusion allows the exchange of
intramitochondrial material, whereas the fission process is required to replicate the
mitochondria during cell division, facilitate the transport and distribution of mitochondria, and
allow the isolation of damaged organelles. Mitochondrial mobility is essential for …