Importance Sepsis is present in many hospitalizations that culminate in death. The
contribution of sepsis to these deaths, and the extent to which they are preventable, is
unknown. Objective To estimate the prevalence, underlying causes, and preventability of
sepsis-associated mortality in acute care hospitals. Design, Setting, and Participants Cohort
study in which a retrospective medical record review was conducted of 568 randomly
selected adults admitted to 6 US academic and community hospitals from January 1, 2014 …