The world is witnessing a rapid demographic shift towards an older population, a trend with
major medical, social, economic and political implications. Aging is a multifaceted process,
involving numerous molecular and cellular mechanisms in the context of different organ
systems. A crucial component of aging is a set of functional and structural alterations in the
immune system that can manifest as a decreased ability to fight infection, diminished
response to vaccination, increased incidence of cancer, higher prevalence of autoimmunity …