Sepsis following cancer surgery: the need for early recognition and standardised clinical care

A Hiong, KA Thursky, BW Teh… - Expert Review of Anti …, 2016 - Taylor & Francis
Expert Review of Anti-infective Therapy, 2016Taylor & Francis
Despite the implementation of multimodal bundles of care in hospitalised patients, post-
operative sepsis in patients with cancer still accounts for a significant burden of illness and
substantial healthcare costs. Patients undergoing surgery for cancer are at particular risk of
sepsis due to underlying malignancy, being immunocompromised associated with cancer
management and the complexity of surgical procedures performed. In this review, we
evaluate the burden of illness and risks for sepsis following surgery for cancer. Current …
Abstract
Despite the implementation of multimodal bundles of care in hospitalised patients, post-operative sepsis in patients with cancer still accounts for a significant burden of illness and substantial healthcare costs. Patients undergoing surgery for cancer are at particular risk of sepsis due to underlying malignancy, being immunocompromised associated with cancer management and the complexity of surgical procedures performed. In this review, we evaluate the burden of illness and risks for sepsis following surgery for cancer. Current evidence supporting standardised strategies for sepsis management (including early recognition and resuscitation) is examined together with challenges in implementing quality improvement programs.
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