[HTML][HTML] The complement system: history, pathways, cascade and inhibitors
P Nesargikar, B Spiller, R Chavez - European Journal of …, 2012 - akjournals.com
P Nesargikar, B Spiller, R Chavez
European Journal of Microbiology and Immunology, 2012•akjournals.comSince its discovery in the 19th century, the complement system has developed into a
clinically significant entity. The complement system has been implicated in a variety of
clinical conditions, from autoimmune diseases to ischemia-reperfusion injury in
transplantation. This article charts the historical progress of our understanding of the
complement system and provides a synopsis on the activation pathways and its inherent
regulators.
clinically significant entity. The complement system has been implicated in a variety of
clinical conditions, from autoimmune diseases to ischemia-reperfusion injury in
transplantation. This article charts the historical progress of our understanding of the
complement system and provides a synopsis on the activation pathways and its inherent
regulators.
Since its discovery in the 19th century, the complement system has developed into a clinically significant entity. The complement system has been implicated in a variety of clinical conditions, from autoimmune diseases to ischemia-reperfusion injury in transplantation. This article charts the historical progress of our understanding of the complement system and provides a synopsis on the activation pathways and its inherent regulators.
akjournals.com