DNA damage is any modification to the structure of DNA that alters its coding properties
and/or interferes with cell processes. One major consequence of oxidative stress is DNA
damage, which include base modifications, abasic sites, and strand breaks. A wide variety of
tools are available to measure DNA damage, in particular for the nuclear genome. Some of
the most widely used tools to measure oxidative DNA damage are the comet assay, PCR-
based assays, immunoassays, and mass spectrometry-based approaches. Although the …