Principles and practice of antibiotic stewardship in the ICU

CI Pickens, RG Wunderink - Chest, 2019 - Elsevier
In the face of emerging drug-resistant pathogens and a decrease in the development of new
antimicrobial agents, antibiotic stewardship should be practiced in all critical care units.
Antibiotic stewardship should be a core competency of all critical care practitioners in
conjunction with a formal antibiotic stewardship program (ASP). Prospective audit and
feedback, and antibiotic time-outs, are effective components of an ASP in the ICU. As rapid
diagnostics are introduced in the ICU, assessment of performance and effect on outcomes …