Severe combined immunodeficiency disorders

IK Chinn, WT Shearer - Immunology and Allergy Clinics, 2015 - immunology.theclinics.com
Severe combined immunodeficiency disorders are characterized by a lack of protective T-, B-
, and sometimes NK-cell responses to infections. As a result, affected individuals are born
with marked susceptibility to pathogens that ultimately cannot be Disclosures: Drs IK Chinn
and WT Shearer have no conflicts of interest to disclose. Section of Immunology, Allergy,
and Rheumatology, Department of Pediatrics, Texas Children's Hospital, Baylor College of
Medicine, 1102 Bates Avenue, Suite 330, Houston, TX 77030-2399, USA