Gastrointestinal (GI) motility function and its regulation is a complex process involving
collaboration and communication of multiple cell types such as enteric neurons, interstitial
cells of Cajal (ICC), and smooth muscle cells. Recent advances in GI research made a better
understanding of ICC function and their role in the GI tract, and studies based on different
types of techniques have shown that ICC, as an integral part of the GI neuromuscular
apparatus, transduce inputs from enteric motor neurons, generate intrinsic electrical …