Despite recent medical advances, atherosclerosis is a global burden accounting for
numerous deaths and hospital admissions. Immune-mediated inflammation is a major
component of the atherosclerotic process, but earlier research focus on adaptive immunity
has gradually switched towards the role of innate immunity. The complement system and toll-
like receptors (TLRs), and the crosstalk between them, may be of particular interest both with
respect to pathogenesis and as therapeutic targets in atherosclerosis. Animal studies …