Electroretinographic abnormalities in a rat glaucoma model with chronic elevated intraocular pressure

AU Bayer, J Danias, S Brodie, KP Maag, B Chen… - Experimental eye …, 2001 - Elsevier
The purpose of this study was to determine the ability of electroretinographic (ERG)
measurements to document progression of the retinopathy in a rat glaucoma model. Thirty
four rats with a chronic intraocular pressure (IOP) elevation induced in one eye by cautery of
three episcleral/extra-orbital veins were studied in four separate groups. ERGs were
recorded sequentially in Group A rats (n= 12) at baseline, and after approximately 20, 40
and 60 days of high IOP, and in three additional groups of rats (n= 6 or 10 per group) after …