[HTML][HTML] Microvesicles as novel biomarkers and therapeutic targets in transplantation medicine

F Fleissner, Y Goerzig, A Haverich, T Thum - American Journal of …, 2012 - Elsevier
Microvesicles (MVs) including exosomes are emerging new biomarkers and potential
regulators of inflammation and immunological processes. Such particles contain proteins
and genetic information including DNA and microRNAs that may be of importance for
cell/cell communication. However, their role during and after organ transplantation and
immunomodulatory effects is only in its beginning of understanding. We here, in brief,
introduce generation and biological importance of MVs, describe their (patho) physiological …