BACKGROUND/AIMS: The Peroxisome Proliferator-Activated Receptor (PPAR) α belongs to
the superfamily of Nuclear Receptors and plays an important role in numerous cellular
processes, including lipid metabolism. It is known that PPARα also has an anti-inflammatory
effect, which is mainly achieved by down-regulating pro-inflammatory genes. The objective
of this study was to further characterize the role of PPARα in inflammatory gene regulation in
liver. RESULTS: According to Affymetrix micro-array analysis, the expression of various …