[PDF][PDF] Signalling to actin: the Cdc42-N-WASP-Arp2/3 connection
MF Carlier, A Ducruix, D Pantaloni - Chemistry & biology, 1999 - cell.com
MF Carlier, A Ducruix, D Pantaloni
Chemistry & biology, 1999•cell.comThe molecular link between the signalling pathway regulating the formation of filopodia and
the initiation of local actin polymerization has been elucidated: N-WASP, a close homologue
of WASP, which is the product of the gene responsible for the Wiskott-Aldrich syndrome,
mediates a direct connection between the small G-protein Cdc42 and the Arp2/3 complex.
the initiation of local actin polymerization has been elucidated: N-WASP, a close homologue
of WASP, which is the product of the gene responsible for the Wiskott-Aldrich syndrome,
mediates a direct connection between the small G-protein Cdc42 and the Arp2/3 complex.
The molecular link between the signalling pathway regulating the formation of filopodia and the initiation of local actin polymerization has been elucidated: N-WASP, a close homologue of WASP, which is the product of the gene responsible for the Wiskott-Aldrich syndrome, mediates a direct connection between the small G-protein Cdc42 and the Arp2/3 complex.
cell.com