Thymic stromal lymphopoietin–induced human asthmatic airway epithelial cell proliferation through an IL-13–dependent pathway
A Semlali, E Jacques, L Koussih, AS Gounni… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Thymic stromal lymphopoietin (TSLP) plays a pivotal role in the initiation of
allergic airway inflammation. This cytokine is produced by several cell types, including
human epithelial cells. OBJECTIVE: We sought to determine the effect of TSLP on
proliferation and repair of epithelial cells isolated from asthmatic patients and healthy
subjects. METHODS: Expression of TSLP receptor (TSLPR) and its response to inhaled
corticosteroids was evaluated on bronchial biopsy specimens of healthy control subjects …
allergic airway inflammation. This cytokine is produced by several cell types, including
human epithelial cells. OBJECTIVE: We sought to determine the effect of TSLP on
proliferation and repair of epithelial cells isolated from asthmatic patients and healthy
subjects. METHODS: Expression of TSLP receptor (TSLPR) and its response to inhaled
corticosteroids was evaluated on bronchial biopsy specimens of healthy control subjects …