[PDF][PDF] E2F7 and E2F8 keep the E2F family in balance
NS Moon, N Dyson - Developmental cell, 2008 - cell.com
NS Moon, N Dyson
Developmental cell, 2008•cell.comAn article by Li and colleagues (in this issue of Developmental Cell) shows that the atypical
E2Fs, E2F7 and E2F8, are critical for mouse development. One of the important functions of
these family members stems from a negative feedback loop in which E2F7 and E2F8 limit
the expression of E2F1 and prevent E2F1-dependent apoptosis.
E2Fs, E2F7 and E2F8, are critical for mouse development. One of the important functions of
these family members stems from a negative feedback loop in which E2F7 and E2F8 limit
the expression of E2F1 and prevent E2F1-dependent apoptosis.
An article by Li and colleagues (in this issue of Developmental Cell) shows that the atypical E2Fs, E2F7 and E2F8, are critical for mouse development. One of the important functions of these family members stems from a negative feedback loop in which E2F7 and E2F8 limit the expression of E2F1 and prevent E2F1-dependent apoptosis.
cell.com
