A clinical perspective of necrotizing enterocolitis: past, present, and future

R Sharma, ML Hudak - Clinics in perinatology, 2013 - perinatology.theclinics.com
In 1823, Charles Billard described what could be argued to be the first case report of
necrotizing enterocolitis (NEC) as gangrenous enterocolitis in a small weak infant with
infection, inflammation, and necrosis of the gastrointestinal tract (GIT). 1 This report was
followed in 1850 by a publication of a series of 25 term and preterm