Urinary excretion of Tamm-Horsfall protein in women with recurrent urinary tract infections
H Reinhart, N Obedeanu, T Hooton, W Stamm… - The Journal of …, 1990 - Elsevier
Since MS-fimbriated bacteria adhere to Tamm-Horsfall protein, it has been suggested that
Tamm-Horsfall protein may trap urinary pathogens and prevent them from colonizing the
mucosal surfaces of the urinary tract. To test the hypothesis that low urinary Tamm-Horsfall
protein excretion rates predispose to urinary tract infection we obtained serial urine samples
from 17 women with and 18 without a history of recurrent urinary tract infection. None of the
women had known structural abnormalities of the urinary tract. Concentrations of Tamm …
Tamm-Horsfall protein may trap urinary pathogens and prevent them from colonizing the
mucosal surfaces of the urinary tract. To test the hypothesis that low urinary Tamm-Horsfall
protein excretion rates predispose to urinary tract infection we obtained serial urine samples
from 17 women with and 18 without a history of recurrent urinary tract infection. None of the
women had known structural abnormalities of the urinary tract. Concentrations of Tamm …