GABAergic tonic inhibition of substantia gelatinosa neurons in mouse spinal cord
A Takahashi, T Mashimo, I Uchida - Neuroreport, 2006 - journals.lww.com
We used whole-cell recording to identify, for the first time, GABAergic tonic current in
subpopulations of substantia gelatinosa neurons in mouse spinal cord slices. Application of
the γ-aminobutyric acid type A receptor antagonist bicuculline revealed tonic currents in 49
of 73 substantia gelatinosa neurons. These tonic currents were dissected into three groups
according to their diverse pharmacological properties. In the first group, furosemide failed to
block the tonic current while midazolam and propofol potentiated it. In the second group …
subpopulations of substantia gelatinosa neurons in mouse spinal cord slices. Application of
the γ-aminobutyric acid type A receptor antagonist bicuculline revealed tonic currents in 49
of 73 substantia gelatinosa neurons. These tonic currents were dissected into three groups
according to their diverse pharmacological properties. In the first group, furosemide failed to
block the tonic current while midazolam and propofol potentiated it. In the second group …
