Tranexamic acid in control of primary hemorrhage during transurethral prostatectomy

A Rannikko, A Pétas, K Taari - Urology, 2004 - Elsevier
OBJECTIVES: To determine whether short-term treatment of patients about to undergo
transurethral resection of the prostate (TURP) with tranexamic acid (TXA) would be
beneficial in reducing the associated blood loss. METHODS: A prospective and randomized
trial was conducted with 136 men requiring TURP for obstructive urinary symptoms. The
treatment group received 2 g TXA three times daily on the day of, and first day after, the
operation. RESULTS: Short-term TXA treatment significantly reduced the operative blood …