BCL2 and BCL3 are recurrent translocation partners of the IGH locus
N Szymanowska, W Klapper, S Gesk, R Küppers… - Cancer genetics and …, 2008 - Elsevier
Chromosomal translocations affecting the immunoglobulin heavy chain (IGH) locus in
chromosomal band 14q32 are the most frequent cytogenetic changes in B-cell lymphomas.
We studied the presence of IGH translocations in a consecutively ascertained series of 94
classical Hodgkin lymphomas (cHL) by combined immunofluorescence for CD30 and
interphase cytogenetics (FICTION technique). The Hodgkin and Reed–Sternberg cells of a
total of 11 of 87 evaluable cases (13%) showed signal patterns indicative of IGH …
chromosomal band 14q32 are the most frequent cytogenetic changes in B-cell lymphomas.
We studied the presence of IGH translocations in a consecutively ascertained series of 94
classical Hodgkin lymphomas (cHL) by combined immunofluorescence for CD30 and
interphase cytogenetics (FICTION technique). The Hodgkin and Reed–Sternberg cells of a
total of 11 of 87 evaluable cases (13%) showed signal patterns indicative of IGH …
