Microparticle-associated tissue factor activity in cancer patients with and without thrombosis
MET Tesselaar, F Romijn, IK Van Der Linden… - Journal of Thrombosis …, 2009 - jthjournal.org
In a previous study [1], we found that the tissue factor (TF) activity of microparticles (MP)
isolated from platelet-poor plasma (MP-TF activity) was markedly increased in patients with
breast and pancreatic adenocarcinoma who presented with venous thromboembolism
(VTE). Based on these findings, we questioned whether MP-TF activity is also associated
with VTE and survival in unselected patients with a broad spectrum of different types of
cancer. We addressed this question by studying MP-TF activity in consecutive patients with …
isolated from platelet-poor plasma (MP-TF activity) was markedly increased in patients with
breast and pancreatic adenocarcinoma who presented with venous thromboembolism
(VTE). Based on these findings, we questioned whether MP-TF activity is also associated
with VTE and survival in unselected patients with a broad spectrum of different types of
cancer. We addressed this question by studying MP-TF activity in consecutive patients with …