[HTML][HTML] Genetics of venous thrombosis
FR Rosendaal, PH Reitsma - Journal of Thrombosis and Haemostasis, 2009 - Elsevier
Venous thrombosis (deep vein thrombosis, pulmonary embolism) is a common and serious
disorder, with genetic and acquired risk factors. The genetic risk factors can be subdivided in
to those that are strong, moderate and weak. Strong risk factors are deficiencies of
antithrombin, protein C and protein S. Moderately strong are factor V Leiden, prothrombin
20210A, non-O blood group and fibrinogen 10034T. There are many weak genetic risk
factors, including fibrinogen, factor XIII and factor XI variants. Even for moderately strong risk …
disorder, with genetic and acquired risk factors. The genetic risk factors can be subdivided in
to those that are strong, moderate and weak. Strong risk factors are deficiencies of
antithrombin, protein C and protein S. Moderately strong are factor V Leiden, prothrombin
20210A, non-O blood group and fibrinogen 10034T. There are many weak genetic risk
factors, including fibrinogen, factor XIII and factor XI variants. Even for moderately strong risk …