[HTML][HTML] Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: in vivo and in vitro analyses
Y Fudaba, TR Spitzer, J Shaffer, T Kawai, T Fehr… - American journal of …, 2006 - Elsevier
Six patients with renal failure due to multiple myeloma (MM) received simultaneous kidney
and bone marrow transplantation (BMT) from HLA-identical sibling donors following
nonmyeloablative conditioning, including cyclophosphamide (CP), peritransplant
antithymocyte globulin and thymic irradiation. Cyclosporine (CyA) was given for
approximately 2 months posttransplant, followed by donor leukocyte infusions. All six
patients accepted their kidney grafts long-term. Three patients lost detectable chimerism but …
and bone marrow transplantation (BMT) from HLA-identical sibling donors following
nonmyeloablative conditioning, including cyclophosphamide (CP), peritransplant
antithymocyte globulin and thymic irradiation. Cyclosporine (CyA) was given for
approximately 2 months posttransplant, followed by donor leukocyte infusions. All six
patients accepted their kidney grafts long-term. Three patients lost detectable chimerism but …
