Focal adhesion kinase (FAK) is one of the central signaling molecules found at focal
adhesion sites, which are specific areas on the cell membrane where cells attach to
extracellular matrix proteins. Focal adhesion kinase interacts with multiple signaling and
adaptor molecules and effects several signaling pathways. Overexpression of FAK and its
substrate c-Src has been implicated in malignant transformation and acquisition of an
invasive tumor phenotype of different tissues. Overexpression of the multidomain protein …