Patrick Y. Lu, QQ Tang, FY Xie, J. Xu, Y. Liu, PV Scaria, A. Aslam, MC Woodle. Intradigm
Corporation, Rockville, MD. Cancer and many other serious diseases are characterized by
the uncontrolled growth of new blood vessels. Recently, RNA interference (RNAi) has
reinvigorated the therapeutic prospects for inhibiting gene expression and promises many
advantages over binding inhibitors, including high specificity, which is essential for targeted
therapeutics. The modulation of angiogenesis pathways using small interfering RNA …