The identification of cholesterol as a constituent of atheromatous plaques has aroused
recurrent waves of suspicion that lipid metabolism is in some way responsible for the
development of atherosclerosis and coronary artery disease. Lipids are transported in serum
as constituents of three major classes of compounds: cholesterol and its esters,
phospholipids, and triglycerides or neutral fat. Most investigations in recent years have
centered about the notion that serum cholesterol plays a causative role in the development …