Community-acquired meticillin-resistant Staphylococcus aureus: an emerging threat

N Zetola, JS Francis, EL Nuermberger… - The Lancet infectious …, 2005 - thelancet.com
N Zetola, JS Francis, EL Nuermberger, WR Bishai
The Lancet infectious diseases, 2005thelancet.com
Community-acquired meticillin-resistant Staphylococcus aureus (MRSA) is becoming an
important public-health problem. New strains of S aureus displaying unique combinations of
virulence factors and resistance traits have been associated with high morbidity and
mortality in the community. Outbreaks of epidemic furunculosis and cases of severe invasive
pulmonary infections in young, otherwise healthy people have been particularly noteworthy.
We review the characteristics of these new strains of community-acquired MRSA that have …
Summary
Community-acquired meticillin-resistant Staphylococcus aureus (MRSA) is becoming an important public-health problem. New strains of S aureus displaying unique combinations of virulence factors and resistance traits have been associated with high morbidity and mortality in the community. Outbreaks of epidemic furunculosis and cases of severe invasive pulmonary infections in young, otherwise healthy people have been particularly noteworthy. We review the characteristics of these new strains of community-acquired MRSA that have contributed to their pathogenicity and discuss new approaches to the diagnosis and management of suspected and confirmed community-acquired MRSA infections.
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