Glycosylphosphatidylinositol-anchored proteins (GPI-APs) are a functionally and structurally
diverse family of post-translationally modified membrane proteins found mostly in the outer
leaflet of the plasma membrane in a variety of eukaryotic cells. Although the general role of
GPI-APs remains unclear, they have attracted attention because they act as enzymes and
receptors in cell adhesion, differentiation, and host-pathogen interactions. GPI-APs may
represent potential diagnostic and therapeutic targets in humans and are interesting in plant …