p40phox is phosphorylated on threonine 154 and serine 315 during activation of the phagocyte NADPH oxidase: implication of a protein kinase C-type kinase in the …
AP Bouin, N Grandvaux, PV Vignais, A Fuchs - Journal of Biological …, 1998 - ASBMB
The superoxide-generating NADPH oxidase complex of phagocytic cells is a
multicomponent system containing a membrane-bound flavocytochrome b and a small G
protein Rac as well as cytosolic factors p67 phox (phagocyte oxidase), p47 phox, and p40
phox, which translocate to the membrane upon activation. In a previous paper, we reported
that p40 phox undergoes phosphorylation on multiple sites upon stimulation of the NADPH
oxidase by either phorbol 12-myristate 13-acetate or by formyl peptide with a time course …
multicomponent system containing a membrane-bound flavocytochrome b and a small G
protein Rac as well as cytosolic factors p67 phox (phagocyte oxidase), p47 phox, and p40
phox, which translocate to the membrane upon activation. In a previous paper, we reported
that p40 phox undergoes phosphorylation on multiple sites upon stimulation of the NADPH
oxidase by either phorbol 12-myristate 13-acetate or by formyl peptide with a time course …
