Diffusion tensor imaging and tractography of human brain development

P Mukherjee, RC McKinstry - Neuroimaging Clinics, 2006 - neuroimaging.theclinics.com
19 macromolecules, such as myelin [1, 2]. In particular, T1 and T2 relaxation times become
shorter as myelination progresses, allowing visualization of white matter maturation in
infants and children. The T1-weighted hyperintensity and T2-weighted hypointensity of white
matter myelination are first seen in the brain stem and cerebellum of preterm infants as
young as 25 gestational weeks. These MR imaging features of myelination extend
throughout the cerebral white matter during the first 2 years of postterm life in a stereotypical …