Splenic histopathological patterns in chronic myelomonocytic leukemia with clinical correlations: reinforcement of the heterogeneity of the syndrome
DP Steensma, A Tefferi, CY Li - Leukemia research, 2003 - Elsevier
The syndrome of chronic myelomonocytic leukemia (CMML) includes a heterogeneous
group of patients who exhibit both myelodysplastic and myeloproliferative
clinicopathological features. Troublesome splenomegaly is uncommon in myelodysplastic
syndrome (MDS), but when organomegaly occurs, this complication is more likely to be
associated with myelodysplastic–myeloproliferative overlap syndromes such as CMML
rather than “dysplasia-only” MDS types such as refractory anemia. We report a single …
group of patients who exhibit both myelodysplastic and myeloproliferative
clinicopathological features. Troublesome splenomegaly is uncommon in myelodysplastic
syndrome (MDS), but when organomegaly occurs, this complication is more likely to be
associated with myelodysplastic–myeloproliferative overlap syndromes such as CMML
rather than “dysplasia-only” MDS types such as refractory anemia. We report a single …
