[HTML][HTML] Activation of pro-gelatinase B by endometase/matrilysin-2 promotes invasion of human prostate cancer cells
YG Zhao, AZ Xiao, RG Newcomer, HI Park… - Journal of Biological …, 2003 - ASBMB
This work has explored a putative biochemical mechanism by which endometase/matrilysin-
2/matrix metalloproteinase-26 (MMP-26) may promote human prostate cancer cell invasion.
Here, we showed that the levels of MMP-26 protein in human prostate carcinomas from
multiple patients were significantly higher than those in prostatitis, benign prostate
hyperplasia, and normal prostate glandular tissues. The role of MMP-26 in prostate cancer
progression is unknown. MMP-26 was capable of activating pro-MMP-9 by cleavage at the …
2/matrix metalloproteinase-26 (MMP-26) may promote human prostate cancer cell invasion.
Here, we showed that the levels of MMP-26 protein in human prostate carcinomas from
multiple patients were significantly higher than those in prostatitis, benign prostate
hyperplasia, and normal prostate glandular tissues. The role of MMP-26 in prostate cancer
progression is unknown. MMP-26 was capable of activating pro-MMP-9 by cleavage at the …