Bone resorption restored in osteopetrotic mice by transplants of normal bone marrow and spleen cells
DG Walker - Science, 1975 - science.org
DG Walker
Science, 1975•science.orgCapacity to resorb bone and calcified cartilage was restored permanently in mice with
inherited osteopetrosis by the intravenous administration of cell suspensions prepared from
spleen and bone marrow of normal littermates. Beginning near active growth plates as early
as 2 weeks after transplantation, replacement of the abnormal spongiosa continued until
medullary cavities were fully expanded.
inherited osteopetrosis by the intravenous administration of cell suspensions prepared from
spleen and bone marrow of normal littermates. Beginning near active growth plates as early
as 2 weeks after transplantation, replacement of the abnormal spongiosa continued until
medullary cavities were fully expanded.
Capacity to resorb bone and calcified cartilage was restored permanently in mice with inherited osteopetrosis by the intravenous administration of cell suspensions prepared from spleen and bone marrow of normal littermates. Beginning near active growth plates as early as 2 weeks after transplantation, replacement of the abnormal spongiosa continued until medullary cavities were fully expanded.
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