Are prenyl groups on proteins sticky fingers or greasy handles?
This Commentary discusses the work of Dietrich et al. in this issue of the Biochemical
Journal, which sheds new light on the biological roles of protein-bound prenyl groups by
providing evidence that the alpha-subunit of the heterotrimeric G-protein transducin has a
binding site for the geranylgeranyl group of the gamma-subunit.
Journal, which sheds new light on the biological roles of protein-bound prenyl groups by
providing evidence that the alpha-subunit of the heterotrimeric G-protein transducin has a
binding site for the geranylgeranyl group of the gamma-subunit.
Abstract
This Commentary discusses the work of Dietrich et al. in this issue of the Biochemical Journal, which sheds new light on the biological roles of protein-bound prenyl groups by providing evidence that the alpha-subunit of the heterotrimeric G-protein transducin has a binding site for the geranylgeranyl group of the gamma-subunit.
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