Infancy-onset diabetes mellitus and multiple epiphyseal dysplasia
CD Wolcott, ML Rallison - The Journal of pediatrics, 1972 - Elsevier
CD Wolcott, ML Rallison
The Journal of pediatrics, 1972•ElsevierThree siblings with onset of diabetes mellitus infancy are reported. Two (and possibly all
three) of the children also had multiple epiphyseal dysplasia. Demineralization of the bone
with multiple fractures, tooth discoloration, and skin abnormalities were also observed. A
unifying biochemical or physiologic mechanism for the simultaneous appearance of
diabetes, epiphyseal dysplasia, and possible ectodermal dysplasia has not suggested itself,
but this may represent a new syndrome.
three) of the children also had multiple epiphyseal dysplasia. Demineralization of the bone
with multiple fractures, tooth discoloration, and skin abnormalities were also observed. A
unifying biochemical or physiologic mechanism for the simultaneous appearance of
diabetes, epiphyseal dysplasia, and possible ectodermal dysplasia has not suggested itself,
but this may represent a new syndrome.
Summary
Three siblings with onset of diabetes mellitus infancy are reported. Two (and possibly all three) of the children also had multiple epiphyseal dysplasia. Demineralization of the bone with multiple fractures, tooth discoloration, and skin abnormalities were also observed. A unifying biochemical or physiologic mechanism for the simultaneous appearance of diabetes, epiphyseal dysplasia, and possible ectodermal dysplasia has not suggested itself, but this may represent a new syndrome.
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