Immediate post-transplant nephrosis in a patient with congenital nephrotic syndrome

SS Barayan, SI Al-Akash, M Malekzadeh, JL Marik… - Pediatric …, 2001 - Springer
SS Barayan, SI Al-Akash, M Malekzadeh, JL Marik, AH Cohen, RB Ettenger, O Yadin
Pediatric Nephrology, 2001Springer
A 19-month-old girl with congenital nephrotic syndrome of the Finnish type underwent a
living-related renal transplant; 24 h after transplantation she became massively nephrotic.
She did not respond to steroids, plasmapheresis, and high-dose cyclosporine. A month later,
a renal biopsy showed only glomerular foot process effacement. She was treated with high-
dose methylprednisolone pulses and oral cyclophosphamide. She rapidly went into
complete remission with no further relapses. Graft function has been stable 2 years after …
Abstract
A 19-month-old girl with congenital nephrotic syndrome of the Finnish type underwent a living-related renal transplant; 24 h after transplantation she became massively nephrotic. She did not respond to steroids, plasmapheresis, and high-dose cyclosporine. A month later, a renal biopsy showed only glomerular foot process effacement. She was treated with high-dose methylprednisolone pulses and oral cyclophosphamide. She rapidly went into complete remission with no further relapses. Graft function has been stable 2 years after transplantation.
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